16 days in Europe Itinerary

16 days in Europe Itinerary

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Route & dates

16 days in Europe Itinerary

Start: Prague, Czech Republic
Fly + Drive:  5 h 30 min
1
Wuppertal, Germany
— 2 nights
Drive:  5 h 45 min
2
Amsterdam, The Netherlands
— 5 nights
Fly:  4 h
3
Luxembourg City, Luxembourg
— 4 nights
Fly + Train:  6 h 15 min
4
Brno, Czech Republic
— 4 nights
Drive:  2 h
End: Prague, Czech Republic

2
nights
Wuppertal, Germany

Wuppertal ©
Though its origins date to the 12th century, Wuppertal has been at the forefront of technological development since the German Empire.
On the 1st (Fri), don't miss a visit to Historische Stadthalle Wuppertal. Get ready for a full day of sightseeing on the 2nd (Sat): see human ingenuity at work at Lingesetalsperre, admire the striking features of Stadtbucherei Ludenscheid, then visit Sauerlaender Kleinbahn, and finally steep yourself in history at LWL-Industriemuseum Zeche Nachtigall.

To find other places to visit, more things to do, traveler tips, and more tourist information, use the Wuppertal online attractions planner .

Prague, Czech Republic to Wuppertal is an approximately 5.5-hour combination of flight and car. You can also drive. Finish your sightseeing early on the 3rd (Sun) to allow enough time to travel to Amsterdam.

Things to do in Wuppertal

Parks Historic Sites Neighborhoods

Side Trips

Stadtbucherei Ludenscheid, LWL-Industriemuseum Zeche Nachtigall, Sauerlaender Kleinbahn, Lingesetalsperre
Find places to stay May 1 — 3:
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Lingesetalsperre ©
Lingesetalsperre
Historische Stadthalle Wuppertal ©
Historische Stadthalle Wuppertal
Springbrunnen ©

5
nights
Amsterdam, The Netherlands

Amsterdam ©
Known as one of the greatest small cities in the world, Amsterdam charms visitors with its cool and cozy atmosphere.
Amsterdam is known for museums, nightlife, and breweries & distilleries. Your plan includes some of its best attractions: explore the world behind art at Van Gogh Museum, engage your brain at NEMO Science Museum, learn about wildlife with up-close encounters at ARTIS, and hunt for treasures at Albert Cuyp Market.

To see reviews, maps, photos, and more tourist information, go to the Amsterdam trip planning website .

Drive from Wuppertal to Amsterdam in 3 hours. In May, plan for daily highs up to 20°C, and evening lows to 10°C. Finish your sightseeing early on the 8th (Fri) to allow enough time to travel to Luxembourg City.

Things to do in Amsterdam

Museums Historic Sites Neighborhoods
Find places to stay May 3 — 8:
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Van Gogh Museum ©
Van Gogh Museum
Anne Frank House ©
Anne Frank House
Rijksmuseum ©
Rijksmuseum

4
nights
Luxembourg City, Luxembourg

Luxembourg City ©
While Luxembourg City boasts the shiny headquarters of several European institutions and EU offices, it is also home to a beautiful old town that's designated as a World Heritage Site.
You'll find plenty of places to visit near Luxembourg City: Stadtpark Echternach (in Echternach), MNHM Musee National d'Histoire Militaire (in Diekirch) and Mullerthal Trail (in Mullerthal). And it doesn't end there: steep yourself in history at Chateau de Vianden, step into the grandiose world of Palace of the Grand Dukes (Palais Grand-Ducal), contemplate in the serene atmosphere at Notre Dame Cathedral (Cathedrale Notre Dame), and take in the dramatic natural features at Casemates du Bock.

To find ratings, reviews, photos, and tourist information, read our Luxembourg City trip planner.

Traveling by flight from Amsterdam to Luxembourg City takes 4 hours. Alternatively, you can drive; or do a combination of flight and train. In May, daytime highs in Luxembourg City are 20°C, while nighttime lows are 9°C. Finish your sightseeing early on the 12th (Tue) so you can travel to Brno.

Things to do in Luxembourg City

Historic Sites Parks Museums

Side Trips

Echternach, Mullerthal Trail, MNHM Musee National d'Histoire Militaire, Chateau de Vianden, Parc Merveilleux
Find places to stay May 8 — 12:
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Chateau de Vianden ©
Chateau de Vianden
Mullerthal Trail ©
Mullerthal Trail
Le Chemin de la Corniche ©
Le Chemin de la Corniche

4
nights
Brno, Czech Republic

Brno ©
A thousand years old, Brno offers a convenient urban base for exploring the southern section of Moravia, famed for its lush vineyards and natural caves.
Get out of town with these interesting Brno side-trips: Radnice (in Jihlava), Telc (Church of St James the Greater & Church of St. James (Kostel sv. Jakuba)) and Znojmo (City Park, Radnicni vez, &more). The adventure continues: explore the fascinating underground world of Moravian Karst, look for gifts at Campus Square Brno, examine the collection at Retro Muzeum Na Statku, and don't miss a visit to Labyrinth Under the Vegetable Market.

For traveler tips, other places to visit, more things to do, and more tourist information, use the Brno day trip planning website .

You can do a combination of flight and train from Luxembourg City to Brno in 6.5 hours. Other options are to fly; or drive. In May, daily temperatures in Brno can reach 22°C, while at night they dip to 11°C. Finish up your sightseeing early on the 16th (Sat) so you can go by car back home.

Things to do in Brno

Historic Sites Parks Nature

Side Trips

Znojmo, Telc, Radnice, Moravian Karst
Find places to stay May 12 — 16:
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