3 days in Northeast Missouri Itinerary

Test the local claim that Saint Louis is second only to Washington, D.C. in the number of free activities available by spending your holiday exploring the city's central neighborhoods, famous for their restored century-old red-brick buildings.

Saint Louis is known for sightseeing, museums, and zoos & aquariums. Your trip includes some of its best attractions: take in the architecture and atmosphere at Cathedral Basilica of Saint Louis, see the interesting displays at City Museum, learn the secrets of beer at a beer tour and tasting, and relax in the rural setting at Grant’s Farm.

To see more things to do, traveler tips, and other tourist information, use the Saint Louis online journey planner.

Chicago to Saint Louis is an approximately 3-hour flight. You can also drive; or take a train. Expect a bit warmer weather when traveling from Chicago in November: highs in Saint Louis hover around 56°F, while lows dip to 35°F. Cap off your sightseeing on the 22nd (Fri) early enough to catch the flight back home.